Bishop Donahue Memorial High School was a private, Roman Catholic high school in McMechen, West Virginia. It was part of the Roman Catholic Diocese of Wheeling-Charleston. It was named after Patrick James Donahue (1849–1922), who was the third Bishop of the Diocese of Wheeling from 1894 until his death in 1922.
At the end of the 2016-2017 school year, Bishop Donahue High School closed. It was opened for 62 school years (1955 - 2017) and graduated 59 classes (1959 - 2017).