The Roman Catholic Diocese of Penonomé (erected 18 December 1993) is a suffragan diocese of the Archdiocese of Panamá.
Ordinaries
- Uriah Adolphus Ashley Maclean (1993 – 2014), appointed Titular Bishop of Agbia
- Edgardo Muñoz Cedeño, S.V.D. (2015 – Present)